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It prevents progression of anemia and nerve damage by supplying B directly, even when intrinsic factor (the gastric protein needed for oral B12 absorption) is lacking

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10.1074/jbc.TM117.000257 63

Low B6 or reduced activation to P5P can lower GABA production and increase seizure or anxiety susceptibility in some people

BSCG tests for more than 400 drugs on the WADA Prohibited List, 25% more than other leading third-party certification providers that cover less than 300